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14th Symposium on Pharmacokinetics and Drug Metabolism

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Drug Targeting– Challenges in evaluating pharmacokinetic, pharmacodynamics and safety aspects of drug targeting

The Section of Pharmacokinetics and Drug Metabolism within the Swedish Pharmaceutical Society is pleased to welcome you to the 14th Symposium on Pharmacokinetics and Drug Metabolism (previously known as the “Rosenön meeting”). The aim of the Symposium series is to highlight hot topics within the field.

Drug Targeting is a collation of methods to actively increase concentration of drug to cells and tissues of interest. Approaches to achieve drug targeting can be done using various approaches, such as drug formulations or conjugating the active drug to a drug targeting ligand. These approaches can improve the therapeutic window for drugs by means of improved safety by mitigation of off- target effects, reduce the therapeutic dose, can expand the drugable target space and have potential to be used for different types of drug modalities (i.e. small molecule, peptides, nucleotide therapeutics). Although, these methods have shown promising effects in pre-clinical and clinical trials they also come with experimental, bioanalytical, data analytical and regulatory challenges to actually demonstrate and study drug targeting. The focus on 14th Symposium is to address the pharmacokinetic, bioanalytical, pharmacodynamics, safety and regulatory aspect of active drug targeting.

Main Topics

✚✚ General understanding of targeted delivery and different strategies for targeted drug delivery
✚✚ Experimental and Measurement techniques for assessing drug targeting
✚✚ Cellular mechanisms of targeting
✚✚ Drug metabolism and targeted drug delivery
✚✚ Data analysis and Pharmacokinetic/PharmacodynamicsFo modelling for assessing drug targeting
✚✚ Safety and regulatory aspects for targeted drug delivery

Who should attend

This multidisciplinary conference will be of interest to anyone engaged in drug discovery and development. Expected participants include academic and industrial scientists as well as regulatory assessors, working on DMPK, toxicology, pharmacodynamics and pharmaceutics. We also encourage students to attend through a favorable student fee.

Speakers

To be updated.

Venue and Date

The symposium will take place at Hotel Gothia Towers in Gothenburg on March 22 and at AstraZeneca Gothenburg on March 23.

Participation fee

The participation fee is 2000 SEK (Academy), 1000 SEK (Ph D students and Post-Doc presenting a poster) and 3000 SEK (Industry), before February 8, 2016. After this date the participation fee is 2500 SEK  (Academy), 1500 SEK (Ph D students and Post-Doc presenting a poster), and 3500 SEK (Industry). All prices excl. VAT.

 The participation fee includes coffee and lunch on  March 22- 23. Accomodation is not included in the  registration fee.

Please register at www.lakemedelsakademin.se

Poster Session

The program includes a poster session, to which all dparticipants may apply. A number of accepted posters may be selected for oral presentation. Please submit your poster abstracts by e-mail to jenny. hagberg@lakemedelsakademin.se. before February 10, 2017.
Please fill in your registration as soon as you have received information regarding acceptance of your abstract.

Sponsors/Exhibitors

We invite you to become one of the sponsors/exhibitors of the 14th Symposium on Pharmacokinetics and Drug Metabolism. To find information about sponsoring and exhibition please visit our web site at www.lakemedelsakademin.se

 

Organizing committee

Rasmus Jansson-Löfmark, AstraZeneca R&D, Gothenburg; Anna Nordmark, MPA, Sweden; Patrik J Andersson, AstraZeneca R&D, Sweden; Laurent Knerr, AstraZeneca R&D, Sweden; Jeremie Boucher, AstraZeneca R&D, Sweden; Niekk Decker, AstraZeneca R&D, Sweden; Suzanne Iverson, Sahlgrenska University Hospital, Gothenburg; Johanna Haglund, MetaSafe, Södertälje; Maria Kjellsson, Uppsala University, Uppsala; Carlos Vaca Falconi, Swedish Academy of Pharmaceutical Sciences, Stockholm.

Inlägget 14th Symposium on Pharmacokinetics and Drug Metabolism dök först upp på Läkemedelsakademin.


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