Analytical Characterization of Therapeutic Proteins
Therapeutic proteins, especially monoclonal antibodies, are in the present time developing fast and dominate globally regarding clinical trials and registrations of new pharmaceutical drugs. Large investments for research and development are planned in many countries. In Sweden the Government, the Wallenberg Foundation, AstraZeneca and GE Healthcare are making large investments. Therapeutic proteins are primarily developed for very serious illnesses like cancer and immunological diseases. Monoclonal antibodies are very large molecules that require the development of new analytical techniques and methods compared to the traditional small molecular drugs. The main purpose of the mini-symposium is to review the state of the art of the analytical tools available and to highlight the needs of new innovative solutions for remaining problems for both the qualitative and quantitative analysis of therapeutic proteins.
Who should attend
The mini-symposium would be of interest to everyone active in the field of discovery and development of therapeutic proteins at both academy and industry.
Main Topics
Internationally recognized specialists on the analysis of therapeutic proteins will give lectures on the following areas:
++ Separation science/mass spectrometry (LC-MS/MS, CE-MS/MS) ++ Biophysical characterization (spectroscopy, X-ray crystallography) ++ Purity (e.g. host cell proteins) ++ Glycan content ++ Stability ++ Aggregation ++ Bispecific antibodies ++ Biosimilars.
Confirned Speakers
Scientists that up to mid-June have accepted an invitation to contribute include: Pat Sandra, Belgium; Christian Neusüss, Germany; Natalia Markova, Sweden; Daniel G. Bracewell, England; Jennifer McManus, Ireland; Alain Beck, France.
POster Session
The Organizing Committee welcomes contributions of posters; more information will be available within short.
Venue and Date
The meeting will take place in Lund, Sweden, on December 5-6. It opens with registration from about 11 hrs on Monday December 5 and ends on Tuesday December 6 at around 13 hrs.
Participation fee
The participation fee is 2000 SEK (Academy), 1000 SEK (Ph D students and Post-Doc presenting a poster) and 4000 SEK (Industry), before October 19, 2016. After this date the participation fee is 2500 SEK (Academy), 1500 SEK (Ph D students and Post-Doc presenting a poster), and 5000 SEK (Industry). All prices excl. VAT.
The participation fee includes coffee and lunch on December 5-6. Accomodation is not included in the registration fee.
Please register at www.lakemedelsakademin.se
Organizing Committee
Douglas Westerlund, Analytical Pharmaceutical Chemistry, Uppsala University; Per-Olof Edlund, SOBI, Sweden; Sara Richardson, AstraZeneca Mölndal, Sweden; Niklas Gustafsson, NovoNordisk, Denmark; Carlos Vaca Falconi, Swedish Academy of Pharmaceutical Sciences, Stockholm.
Inlägget Analytical Characterization of Therapeutic Proteins dök först upp på Läkemedelsakademin.